Neuronal mechanisms of the anoxia-induced network oscillations in the rat hippocampus in vitro.

@article{Dzhala2001NeuronalMO,
  title={Neuronal mechanisms of the anoxia-induced network oscillations in the rat hippocampus in vitro.},
  author={V Dzhala and Ilgam Khalilov and Yehezkel Ben-Ari and Rustem Khazipov},
  journal={The Journal of physiology},
  year={2001},
  volume={536 Pt 2},
  pages={521-31}
}
1. A spindle of fast network oscillations precedes the ischaemia-induced rapid depolarisation in the rat hippocampus in vivo. However, this oscillatory pattern could not be reproduced in slices and the underlying mechanisms remain poorly understood. We have found that anoxia-induced network oscillations (ANOs, 20-40 Hz, lasting for 1-2 min) can be reproduced in the intact hippocampi of postnatal day P7-10 rats in vitro, and we have examined the underlying mechanisms using whole-cell and… CONTINUE READING