Neuronal-glial metabolism under depolarizing conditions. A 13C-n.m.r. study.

  title={Neuronal-glial metabolism under depolarizing conditions. A 13C-n.m.r. study.},
  author={Ronnitte Badar-Goffer and O. Ben-Yoseph and Herman S. Bachelard and Peter G. Morris},
  journal={The Biochemical journal},
  volume={282 ( Pt 1)},
Time courses of incorporation of 13C from 13C-labelled glucose and/or acetate into the individual carbon atoms of amino acids, citrate and lactate in depolarized cerebral tissues were monitored by using 13C-n.m.r. spectroscopy. There was no change in the maximum percentage of 13C enrichments of the amino acids on depolarization, but the maxima were reached more rapidly, indicating that rates of metabolism in both glycolysis and the tricarboxylic acid cycle were accelerated. Although labelling… CONTINUE READING


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