Neuronal expression of glutamine synthetase in Alzheimer's disease indicates a profound impairment of metabolic interactions with astrocytes.

@article{Robinson2000NeuronalEO,
  title={Neuronal expression of glutamine synthetase in Alzheimer's disease indicates a profound impairment of metabolic interactions with astrocytes.},
  author={Stephen R. Robinson},
  journal={Neurochemistry international},
  year={2000},
  volume={36 4-5},
  pages={471-82}
}
A considerable body of evidence indicates that the activity of glutamine synthetase is decreased in the cerebral cortices of brains affected by Alzheimer's disease. It is difficult to discern the reason for this decrease because it is not known whether the cellular distribution of glutamine synthetase is altered in Alzheimer's disease. Therefore the present… CONTINUE READING