Neuronal differentiation of murine bone marrow Thy-1- and Sca-1-positive cells.

@article{Locatelli2003NeuronalDO,
  title={Neuronal differentiation of murine bone marrow Thy-1- and Sca-1-positive cells.},
  author={Federica Locatelli and Stefania Corti and Chiara Donadoni and Michela Guglieri and Franco Capra and Sandra Strazzer and Sabrina Salani and Roberto Del Bo and Francesco Fortunato and Alessandra Bordoni and Giacomo Comi},
  journal={Journal of hematotherapy & stem cell research},
  year={2003},
  volume={12 6},
  pages={727-34}
}
Recent evidence suggests that cells from bone marrow can acquire neuroectodermal phenotypes in cell culture or after transplantation in animal models and in the human brain. However, isolation of the bone marrow cell subpopulation with neuronal differentiation potential remains a challenge. To isolate and expand neural progenitors from whole murine bone marrow, bone marrow was obtained from hind limb bone of C57BL6 mice and plated in culture with neuronal medium with basic fibroblast growth… CONTINUE READING