Neuronal differentiation of hippocampus-derived neural stem cells cultured in conditioned medium of embryonic rat retina.

@article{Kaneko2003NeuronalDO,
  title={Neuronal differentiation of hippocampus-derived neural stem cells cultured in conditioned medium of embryonic rat retina.},
  author={Yumi Kaneko and Masaki Ichikawa and Yasuo Kurimoto and Kouichi Ohta and Nagahisa Yoshimura},
  journal={Ophthalmic research},
  year={2003},
  volume={35 5},
  pages={268-75}
}
PURPOSE To investigate whether conditioned medium from embryonic rat retinas can induce differentiation of adult rat hippocampus-derived neural stem cells (AHSCs) into neurons and glia in vitro. METHODS AHSCs were cultured in 3 types of media: standard culture medium, conditioned medium from embryonic rat retina, and standard culture medium with retinoic acid. Neuronal and glial differentiation of the cultured cells was assessed by cell growth analysis, flow cytometric analysis… CONTINUE READING