Neuronal death in the development and aging of the cerebral cortex of the mouse.

@article{Heumann1981NeuronalDI,
  title={Neuronal death in the development and aging of the cerebral cortex of the mouse.},
  author={Didier Heumann and Genevi{\`e}ve Leuba},
  journal={Neuropathology and applied neurobiology},
  year={1981},
  volume={9 4},
  pages={
          297-311
        }
}
The numbers of neurons and glial cells in the cerebral cortex of the mouse have been estimated during its whole life-span (5 to 720 days), taking into account both the cellular densities of several areas and the cortical volumes. The results clearly demonstrate that there is a massive neuronal loss in the cerebral cortex during early postnatal development, greater in layers II-IV than in layers V-VI. In contrast, aging is characterized by a discrete neuronal loss in the cerebral cortex, purely… CONTINUE READING

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