Neuronal death by repetitive cortical spreading depression in juvenile rat brain.

@article{Sadeghian2012NeuronalDB,
  title={Neuronal death by repetitive cortical spreading depression in juvenile rat brain.},
  author={Homa Sadeghian and Maryam Jafarian and Fariba Karimzadeh and Laya Kafami and Hadi Kazemi and P. G. B. G. M. D. A. S. Coulon and Mojdeh Ghabaee and Ali Gorji},
  journal={Experimental neurology},
  year={2012},
  volume={233 1},
  pages={438-46}
}
Spreading depression (SD) is an intrinsic bioelectrical property of the human central nervous system, which plays a key role in neurological disorders. In the present study, we investigated whether experimentally induced repetitive SD caused neuronal death in cortical and subcortical regions of the juvenile rat brain. The animals were anesthetized and the electrodes as well as a cannula were implanted over the brain. Repetitive cortical SD events were induced by KCl injection. The brains were… CONTINUE READING