Neuronal cytoskeletal abnormalities in human cerebral cortical dysplasia

  title={Neuronal cytoskeletal abnormalities in human cerebral cortical dysplasia},
  author={T. Duong and Michael De Rosa and Vadims Poukens and H V Vinters and Robin Scott Fisher},
  journal={Acta Neuropathologica},
The cytoskeletal abnormalities of cortical neurons in human cerebral cortical dysplasia were compared by immunohistochemical methods to the neurofibrillary tangles of Alzheimer's disease (AD). Surgical specimens from cortical resections performed for the treatment of intractable childhood seizures as well as autopsied samples from AD patients were analyzed with different antibodies directed against high- or medium-molecular mass neurofilament epitopes, phosphorylated or non-phosphorylated forms… CONTINUE READING


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An assessment of the proliferative potential of "balloon cells" in focal cortical resections performed for childhood epilepsy

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3 Excerpts

Fibrillary tangles in hemimegalencephaly and Alzheimer's disease share a common antigen determinant

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Neurofilamentous tangles in the human hemimegalencephalic neocortex

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Neuropathology of hemimegalencephaly: morphologic studies from surgically resected specimens

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