Neuronal cyclin-dependent kinase 5: role in nervous system function and its specific inhibition by the Cdk5 inhibitory peptide.

@article{Kesavapany2004NeuronalCK,
  title={Neuronal cyclin-dependent kinase 5: role in nervous system function and its specific inhibition by the Cdk5 inhibitory peptide.},
  author={Sashi Kesavapany and B Li and Niranjana D. Amin and Ya-li Zheng and Philip Grant and Harish C. Pant},
  journal={Biochimica et biophysica acta},
  year={2004},
  volume={1697 1-2},
  pages={143-53}
}
Cyclin-dependent kinase 5 (Cdk5) is a member of the cyclin-dependent kinase family that is involved in the regulation of the cell cycle. As their name suggests, the Cdks require association with activator proteins called cyclins for their activity. Cdk5, however, is unique to this family of proline-directed serine/threonine kinases on two accounts. Firstly, Cdk5 has not been found to function in the cell cycle and, although expressed in a number of tissues, its activity is restricted to the… CONTINUE READING

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