Neuronal coupling in the developing mammalian retina.

  title={Neuronal coupling in the developing mammalian retina.},
  author={Anna A Penn and Rachel O. L. Wong and Carla J. Shatz},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={14 6},
During the first 3 weeks of postnatal development in the ferret retina, cells in the ganglion cell layer spontaneously generate waves of electrical activity that travel across the retina in the absence of mature photoreceptors (Meister et al., 1991; Wong et al., 1993). Since few chemical synapses are present at the earliest stages when waves are present, we have explored whether gap junctions could act to correlate the activity of cells in the immature ganglion cell layer. Retinal ganglion… CONTINUE READING