Neuronal contact guidance in magnetically aligned fibrin gels: effect of variation in gel mechano-structural properties.

@article{Dubey2001NeuronalCG,
  title={Neuronal contact guidance in magnetically aligned fibrin gels: effect of variation in gel mechano-structural properties.},
  author={Neha Dubey and Paul C. Letourneau and Robert T. Tranquillo},
  journal={Biomaterials},
  year={2001},
  volume={22 10},
  pages={1065-75}
}
Neurite outgrowth from chick dorsal root ganglia entrapped in isotropic and magnetically aligned fibrin gels was studied, and the dependence on the diameter of the fibrin fibrils was characterized. The fibrin fibril diameter was varied, as inferred from turbidity measurements, by using different Ca2+ concentrations in the fibrin-forming solution, but this variation was accomplished without affecting the degree of magnetic-induced alignment, as directly visualized in fluorescently spiked gels… CONTINUE READING

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