Neuronal ceroid-lipofuscinosis in a Holstein steer.

  title={Neuronal ceroid-lipofuscinosis in a Holstein steer.},
  author={Scott Hafner and Thomas Flynn and Barry G. Harmon and Janet E Hill},
  journal={Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc},
  volume={17 2},
A young, partially blind Holstein steer was affected by mild cerebral atrophy. Formalin-fixed cerebral gray matter was diffusely yellow brown. Microscopically, there were eosinophilic, autofluorescent granules primarily in the cytoplasm of cerebral neurons. There was also extensive retinal atrophy with complete loss of the rod and cone layers. Ultrastructural examination of affected cerebral neurons revealed a mixture of granular osmiophilic and lamellar patterns in the cytoplasmic storage… CONTINUE READING
5 Citations
21 References
Similar Papers


Publications referenced by this paper.
Showing 1-10 of 21 references

Similar Papers

Loading similar papers…