Neuronal calcium sensor proteins are direct targets of the insulinotropic agent repaglinide.

@article{Okada2003NeuronalCS,
  title={Neuronal calcium sensor proteins are direct targets of the insulinotropic agent repaglinide.},
  author={Miki Okada and Daisuke Takezawa and Shuji Tachibanaki and Satoru Kawamura and Hiroshi Tokumitsu and Ryoji Kobayashi},
  journal={The Biochemical journal},
  year={2003},
  volume={375 Pt 1},
  pages={87-97}
}
The NCS (neuronal calcium sensor) proteins, including neurocalcins, recoverins and visinin-like proteins are members of a family of Ca2+-sensitive regulators, each with three Ca2+-binding EF-hand motifs. In plants, lily CCaMK [chimaeric Ca2+/CaM (calmodulin)-dependent protein kinase] and its PpCaMK ( Physcomitrella patens CCaMK) homologue are characterized by a visinin-like domain with three EF-hands. In the present study, in an effort to discover NCS antagonists, we screened a total of 43… CONTINUE READING

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Modulation of A - type potassium channels by a family of calcium sensors

D. A. Archer, R. D. Burgoyne
Nature ( London ) • 2000

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