Neuronal apoptosis versus necrosis induced by glutamate or free radicals

Abstract

The type of cell death encountered in neuronal cell cultures exposed to excitatory amino acids — such as glutamate, the major excitatory neurotransmitter in the central nervous system, or free radicals, such as nitric oxide (NO.) and superoxide anoin (O2. −), which react to form peroxynitrite (ONOO−) — appears to depend on the intensity of the exposure and… (More)
DOI: 10.1007/BF00142073

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