Neuronal apoptosis in HIV infection in adults

@article{AdleBiassette1995NeuronalAI,
  title={Neuronal apoptosis in HIV infection in adults},
  author={Homa Adle-Biassette and Yves L{\'e}vy and M. Colornbel and F. Poron and Sevdalin Natchev and Catherine Keohane and Françoise Gray},
  journal={Neuropathology and Applied Neurobiology},
  year={1995},
  volume={21}
}
Productive infection of the central nervous system by HIV predominantly involves the white matter and basal ganglia. Involvement of the cerebral cortex with neuronal loss is also described in AIDS patients but not in asymptomatic HIV‐positive patients. The mechanism of neuronal damage is unknown. To enquire whether neuronal loss in AIDS may be due to an apoptotic process, we examined the cerebral cortex from 12 patients who died from AIDS using two different methods: in situ end labelling and… Expand
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