Neuronal and vascular interactions.

  title={Neuronal and vascular interactions.},
  author={Benjamin J. Andreone and Baptiste Lacoste and Chenghua Gu},
  journal={Annual review of neuroscience},
The brain, which represents 2% of body mass but consumes 20% of body energy at rest, has a limited capacity to store energy and is therefore highly dependent on oxygen and glucose supply from the blood stream. Normal functioning of neural circuits thus relies on adequate matching between metabolic needs and blood supply. Moreover, not only does the brain need to be densely vascularized, it also requires a tightly controlled environment free of toxins and pathogens to provide the proper chemical… CONTINUE READING
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