Neuronal and network activity in networks of cultured spinal motor neurons.

@article{Zhang2009NeuronalAN,
  title={Neuronal and network activity in networks of cultured spinal motor neurons.},
  author={Hong-Mei Zhang and Natallia Robinson and Ilsa G{\'o}mez-Curet and Wenlan Wang and Melissa A Harrington},
  journal={Neuroreport},
  year={2009},
  volume={20 9},
  pages={849-54}
}
This is the first report of multielectrode recordings from networks of cultured motor neurons. Neurons isolated from the ventral horns of spinal cords of E15 rats were cultured on MED64 probes. The majority of the neurons in the cultures are positive for neurofilament, choline acetyltransferase, and Hb9, characteristics of motor neurons. The activity of the motor neuron network is characterized by spiking of individual cells as well as spontaneous, synchronized bursts involving all active… CONTINUE READING