Neuronal and inducible nitric oxide synthase expression and protein nitration in rat cerebellum after oxygen and glucose deprivation.

@article{Rodrigo2001NeuronalAI,
  title={Neuronal and inducible nitric oxide synthase expression and protein nitration in rat cerebellum after oxygen and glucose deprivation.},
  author={J Rodrigo and Dulce Alonso and Ana Patr{\'i}cia O. Fernandez and Julia Serrano and Ana Richart and Juan Carlos L{\'o}pez and Mar{\'i}a Santacana and Ricardo Mart{\'i}nez-Murillo and Mar{\'i}a Luisa Bentura and Marco Ghiglione and Lars Otto Uttenthal},
  journal={Brain research},
  year={2001},
  volume={909 1-2},
  pages={20-45}
}
A perfusion model of global cerebral ischemia was used for the immunohistochemical study of changes in the glutamate-nitric oxide (NO) system in the rat cerebellum and cerebellar nuclei during a 0-14 h reperfusion period after 30 min of oxygen and glucose deprivation, with and without administration of 1.5 mM N(omega)-nitro-L-arginine methyl ester (L-NAME). While immunostaining for N-methyl-D-aspartate receptor subunit 1 (NMDAR1) showed no marked changes during the reperfusion period, neuronal… CONTINUE READING

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