Neuronal and inducible nitric oxide synthase expression and protein nitration in rat cerebellum after oxygen and glucose deprivation

@article{Rodrigo2001NeuronalAI,
  title={Neuronal and inducible nitric oxide synthase expression and protein nitration in rat cerebellum after oxygen and glucose deprivation},
  author={J. Rodrigo and D. Alonso and A. Fern{\'a}ndez and J. Serrano and L. O. Uttenthal},
  journal={Brain Research},
  year={2001},
  volume={909},
  pages={20-45}
}
  • J. Rodrigo, D. Alonso, +2 authors L. O. Uttenthal
  • Published 2001
  • Biology, Medicine
  • Brain Research
  • A perfusion model of global cerebral ischemia was used for the immunohistochemical study of changes in the glutamate-nitric oxide (NO) system in the rat cerebellum and cerebellar nuclei during a 0-14 h reperfusion period after 30 min of oxygen and glucose deprivation, with and without administration of 1.5 mM N(omega)-nitro-L-arginine methyl ester (L-NAME). While immunostaining for N-methyl-D-aspartate receptor subunit 1 (NMDAR1) showed no marked changes during the reperfusion period, neuronal… CONTINUE READING
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