Neuronal and glial localization of the cannabinoid-1 receptor in the superficial spinal dorsal horn of the rodent spinal cord.

@article{Hegyi2009NeuronalAG,
  title={Neuronal and glial localization of the cannabinoid-1 receptor in the superficial spinal dorsal horn of the rodent spinal cord.},
  author={Zolt{\'a}n Hegyi and Gr{\'e}ta Kis and Krisztina Holl{\'o} and Catherine A. Ledent and Miklos Antal},
  journal={The European journal of neuroscience},
  year={2009},
  volume={30 2},
  pages={251-62}
}
A long line of experimental evidence indicates that endogenous cannabinoid mechanisms play important roles in nociceptive information processing in various areas of the nervous system including the spinal cord. Although it is extensively documented that the cannabinoid-1 receptor (CB(1)-R) is strongly expressed in the superficial spinal dorsal horn, its cellular distribution is poorly defined, hampering our interpretation of the effect of cannabinoids on pain processing spinal neural circuits… CONTINUE READING