Neuronal activity-regulated gene transcription in synapse development and cognitive function.

@article{West2011NeuronalAG,
  title={Neuronal activity-regulated gene transcription in synapse development and cognitive function.},
  author={Anne E West and Michael E. Greenberg},
  journal={Cold Spring Harbor perspectives in biology},
  year={2011},
  volume={3 6}
}
Activity-dependent plasticity of vertebrate neurons allows the brain to respond to its environment. During brain development, both spontaneous and sensory-driven neural activity are essential for instructively guiding the process of synapse development. These effects of neuronal activity are transduced in part through the concerted regulation of a set of activity-dependent transcription factors that coordinate a program of gene expression required for the formation and maturation of synapses… CONTINUE READING
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References

Publications referenced by this paper.
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Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 1996
View 14 Excerpts
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Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice.

Proceedings of the National Academy of Sciences of the United States of America • 2009
View 5 Excerpts
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