Neuronal activity in the nucleus accumbens is necessary for performance-related increases in cortical acetylcholine release

@article{Neigh2004NeuronalAI,
  title={Neuronal activity in the nucleus accumbens is necessary for performance-related increases in cortical acetylcholine release},
  author={Gretchen N Neigh and Hannelore Arnold and Rebecca L. Rabenstein and Martin Sarter and John P. Bruno},
  journal={Neuroscience},
  year={2004},
  volume={123},
  pages={635-645}
}
In vivo microdialysis was used to determine the necessity of neuronal activity in the nucleus accumbens (NAC) for task-induced increases in cortical acetylcholine (ACh) efflux. Rats were trained in a behavioral task in which they were required to perform a defined number of licks of a citric acid solution in order to gain access to a palatable, cheese-flavored food. Upon reaching a consistent level of performance, rats were implanted with microdialysis cannula in the medial prefrontal cortex… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 26 CITATIONS

NMDA and dopamine interactions in the nucleus accumbens modulate cortical acetylcholine release.

  • The European journal of neuroscience
  • 2005
VIEW 3 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Attention and the Cholinergic System: Relevance to Schizophrenia.

  • Current topics in behavioral neurosciences
  • 2015
VIEW 1 EXCERPT
CITES BACKGROUND

Time to pay attention: attentional performance time-stamped prefrontal cholinergic activation, diurnality, and performance.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2012
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 57 REFERENCES

Projections from the nucleus accumbens to cholinergic neurons of the ventral pallidum: a correlated light and electron microscopic double-immunolabeling study in rat

L Zaborszky, WE Cullinan
  • Brain Res
  • 1992
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Distinct changes in cortical acetylcholine and noradrenaline efflux during contingent and noncontingent performance of a visual attentional task.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2001
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL