Neuronal SUMOylation: mechanisms, physiology, and roles in neuronal dysfunction.

@article{Henley2014NeuronalSM,
  title={Neuronal SUMOylation: mechanisms, physiology, and roles in neuronal dysfunction.},
  author={Jeremy M Henley and Tim J. Craig and Kevin A. Wilkinson},
  journal={Physiological reviews},
  year={2014},
  volume={94 4},
  pages={1249-85}
}
Protein SUMOylation is a critically important posttranslational protein modification that participates in nearly all aspects of cellular physiology. In the nearly 20 years since its discovery, SUMOylation has emerged as a major regulator of nuclear function, and more recently, it has become clear that SUMOylation has key roles in the regulation of protein trafficking and function outside of the nucleus. In neurons, SUMOylation participates in cellular processes ranging from neuronal… CONTINUE READING

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