Neuronal RNA in nucleus ambiguus and nucleus hypoglossus of patients with amyotrophic lateral sclerosis.

@article{Hartmann1989NeuronalRI,
  title={Neuronal RNA in nucleus ambiguus and nucleus hypoglossus of patients with amyotrophic lateral sclerosis.},
  author={Henrik A. Hartmann and Siobhan McMahon and D. Y. Sun and James H. Abbs and Etsuro Uemura},
  journal={Journal of neuropathology and experimental neurology},
  year={1989},
  volume={48 6},
  pages={669-73}
}
To establish objectively the involvement of neurons in the medulla oblongata in patients with amyotrophic lateral sclerosis (ALS), ribonucleic acid (RNA) content was determined in neurons of the hypoglossal nucleus and the nucleus ambiguus. Neurons from those two nuclei showed a significant loss of RNA content in patients with ALS; only 57% and 38% of the… CONTINUE READING