Neuronal Migration and Ventral Subtype Identity in the Telencephalon Depend on SOX1

@article{Ekonomou2005NeuronalMA,
  title={Neuronal Migration and Ventral Subtype Identity in the Telencephalon Depend on SOX1},
  author={Antigoni Ekonomou and Ilias Kazanis and Stavros Malas and Heather Wood and Pavlos Alifragis and Myrto Denaxa and Domna Karagogeos and Andrew Constanti and Robin Lovell-Badge and Vasso Episkopou},
  journal={PLoS Biology},
  year={2005},
  volume={3},
  pages={646 - 654}
}
Little is known about the molecular mechanisms and intrinsic factors that are responsible for the emergence of neuronal subtype identity. Several transcription factors that are expressed mainly in precursors of the ventral telencephalon have been shown to control neuronal specification, but it has been unclear whether subtype identity is also specified in these precursors, or if this happens in postmitotic neurons, and whether it involves the same or different factors. SOX1, an HMG box… CONTINUE READING
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