Neuronal GABA release and GABA inhibition of ACh release in guinea pig urinary bladder.

@article{Kusunoki1984NeuronalGR,
  title={Neuronal GABA release and GABA inhibition of ACh release in guinea pig urinary bladder.},
  author={Masato Kusunoki and Kohtaro Taniyama and Chikako Tanaka},
  journal={The American journal of physiology},
  year={1984},
  volume={246 4 Pt 2},
  pages={R502-9}
}
gamma-Aminobutyric acid (GABA) and glutamate decarboxylase (GAD) are present in the urinary bladder of guinea pigs, and the possible correlation in regional distribution between GABA, GAD, and the number of vesical ganglion cells was studied. Electrical stimulation of the bladder strips produced an increase in the calcium-dependent and tetrodotoxin-sensitive [3H]GABA release and contractions in the strips preloaded with [3H]GABA. Nicotine, acetylcholine chloride (ACh), and hexamethonium did not… CONTINUE READING

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