Neuronal FLT1 receptor and its selective ligand VEGF-B protect against retrograde degeneration of sensory neurons.

Abstract

Even though VEGF-B is a homologue of the potent angiogenic factor VEGF, its angiogenic activities have been controversial. Intrigued by findings that VEGF-B may also affect neuronal cells, we assessed the neuroprotective and vasculoprotective effects of VEGF-B in the skin, in which vessels and nerves are functionally intertwined. Although VEGF-B and its… (More)
DOI: 10.1096/fj.10-170944

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Cite this paper

@article{Dhondt2011NeuronalFR, title={Neuronal FLT1 receptor and its selective ligand VEGF-B protect against retrograde degeneration of sensory neurons.}, author={Joke Dhondt and Eve Peeraer and A. K. Verheyen and Rony Nuydens and Ian Buysschaert and Koen Poesen and Katie van Geyte and Manu Beerens and Masabumi Shibuya and Jody J. Haigh and Theo Meert and Peter Carmeliet and Diether Lambrechts}, journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology}, year={2011}, volume={25 5}, pages={1461-73} }