Neuronal α-Synucleinopathy with Severe Movement Disorder in Mice Expressing A53T Human α-Synuclein

@article{Giasson2002NeuronalW,
  title={Neuronal α-Synucleinopathy with Severe Movement Disorder in Mice Expressing A53T Human α-Synuclein},
  author={Benoit I Giasson and John Eric Duda and Shawn M. Quinn and Bin Zhang and John Q. Trojanowski and Virginia M. Y. Lee},
  journal={Neuron},
  year={2002},
  volume={34},
  pages={521-533}
}
erative diseases is due to the remarkable discovery that in dominantly inherited ␣-syn substitutions, A53T was found in at least 12 families with familial PD albeit they likely share a common ancestor (Polymeropoulos et al. halo that are detected by conventional histological 2 Parkinson's Disease Research, Education stains, especially in dopaminergic neurons of the sub-and Clinical Center stantia nigra pars compacta (SNpc) of PD patients Philadelphia Veterans Administration Hospital (Forno… CONTINUE READING
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