Neuron theory, the cornerstone of neuroscience, on the centenary of the Nobel Prize award to Santiago Ramón y Cajal

  title={Neuron theory, the cornerstone of neuroscience, on the centenary of the Nobel Prize award to Santiago Ram{\'o}n y Cajal},
  author={Francisco Javier L{\'o}pez-Mu{\~n}oz and Jes{\'u}s Boya and Cecilio {\'A}lamo},
  journal={Brain Research Bulletin},

The renaissance of the neuron doctrine: Cajal rebuts the Rector of Granada

An English translation of Cajal’s Spanish paper is provided, placing it in the context of evolving notions during that first decade of the twentieth century crucial for neurobiology.

Santiago Ramon y Cajal and Neuron Doctrine

Santiago Ramon y Cajal, was a scientist with unusual observation and interpretation talents, who pushed the conditions until the end to access to information and share his findings in the underdeveloped scientific environment of Spain.

Neuron Doctrine and Conditional Reflexes at the XIV International Medical Congress of Madrid of 1903

There is a long tradition of holding meetings to present new ideas or discoveries that help in transforming our world in different areas of science and industry. One of these meetings was the 14th

Robert Bentley Todd's Contribution to Cell Theory and The Neuron Doctrine

Robert Bentley Todd, who is best remembered for “Todd's paralysis,” made many more important contributions to neurology and neuroscience, including the concept of brain electricity and electrical discharges in epilepsy, as described in his textbook The Descriptive and Physiological Anatomy of the Brain, Spinal Cord and Ganglions.

Historical evolution of the neurotransmission concept

This review describes the process of the discovery of the different neurotransmitters and neuroreceptors, and analyse the new interpretations postulated in relation to the neurotransmission concept at the dawn of the twenty-first century.

Historical first descriptions of Cajal–Retzius cells: from pioneer studies to current knowledge

This review will summarize in a temporal basis the emerging knowledge concerning this cell population with specific attention the pioneer studies of Santiago Ramón y Cajal.

Camillo Golgi (1843 –1926): scientist extraordinaire and pioneer figure of modern neurology

  • S. Ghosh
  • Biology
    Anatomy & cell biology
  • 2020
Camillo Golgi was an extraordinary scientist whose contributions in the domain of neuroanatomy proved to be critical for emergence of neuroscience as a sovereign scientific discipline and was jointly awarded the Nobel Prize for Physiology or Medicine in 1906.

La neurofisiología cartesiana: entre los spiritus animalis y el conarium

In the Teatrise of Man, all of the mechanicist physiological Cartesian theories are brought into play, and the human being is assimilated to an artificial robot, with the exception of the superior executive control exerted by the soul.



The Neuron Theory

  • H. Fodstad
  • Biology
    Stereotactic and Functional Neurosurgery
  • 2001
The classic neuron doctrine has served well as the theoretical basis for the great advances in the authors' current understanding of the cellular basis of nervous system functions.

August Forel ‐ Cofounder of the Neuron Theory (1848–1931)

His life long struggle for peace and better living conditions for the sick and the poor have left their traces up to present day, not only for his missionary zeal for birth control and equal rights for women, but also for public innovations such as the opening of non-alcoholic restaurants.

Foundations of the neuron doctrine

The Neuron Doctrine Revisited: A Personal Account - Sten Grillner Camillo Golgi, Foundations of the Neuron doctrine, and the History of Neurosciences - Paolo Mazzarello Some Reflections on the Neurion Doctrine - Larry Swanson.

The Golgi Stain: invention, diffusion and impact on neurosciences.

  • E. Pannese
  • Biology
    Journal of the history of the neurosciences
  • 1999
The black reaction was the first technique to reveal neurons in their entirety, i.e. with all their processes, and is still used extensively not only in combination with electron microscopy, but also in studies on the evolution, ontogeny, and organization of the nervous system.

The early history of the synapse: from plato to sherrington

Integrative Action of the Nervous System

The functions of the Brain and the Theories of their Relation are studied in detail in the second volume of Nick Wade's Mind and Body, which aims to clarify the role of the nervous system in human health.

Discoveries in the Human Brain: Neuroscience Prehistory, Brain Structure, and Function

This chapter discusses the evolution of the Mammalian Brain, modern Theories of Evolutionary Neurology, and Insights from Phylogeny and Embryology, as well as three major Integrative Systems.

Mikroskopische Üntersuchungen über die Übereinstimmung in der Struktur und dem Wachstume der Tiere und Pflanzen

This famous memoir by a distinguished pupil of Johannes Müller converted histology into a rational branch of science and founded the cell-theory upon which modern physiology and pathology are based.


Electron micrographs are presented of synaptic regions encountered in sections of frog sympathetic ganglia and earthworm nerve cord neuropile, and a submicroscopic filamentary component can be seen in the presynaptic member extending up to the region where the vesicles are found, but terminating short of the synapse itself.

Structure et connexions des neurones. Conférence Nobel faite à Stockholm le 12 décembre 1906

I. Les cellules nerveuses sont des individualités morphologiques, des neurones, suivant le mot consacré par l’autorité du prof. Waldeyer. Cette propriété fut déjà démontrée par mon illustre confrère