Neuron-specific human glutamate transporter: molecular cloning, characterization and expression in human brain

  title={Neuron-specific human glutamate transporter: molecular cloning, characterization and expression in human brain},
  author={P. Shashidharan and G. Huntley and T. Meyer and J. Morrison and A. Plaitakis},
  journal={Brain Research},
  • P. Shashidharan, G. Huntley, +2 authors A. Plaitakis
  • Published 1994
  • Biology, Medicine
  • Brain Research
  • A cDNA encoding a neuron-specific glutamate/aspartate transporter was isolated from human brain cDNA libraries and characterized. The new cDNA, designated human glutamate transporter III, is structurally distinct from two previously described brain specific glutamate transporters. This human cDNA is 90% and 95% homologous at nucleotide and amino acid level, respectively, with a previously reported rabbit glutamate/aspartate transporter. Northern blot analysis of human tissues revealed that the… CONTINUE READING
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