Neuron-specific enolase in the diagnosis of neuroblastoma and other small, round-cell tumors in children.

@article{Tsokos1984NeuronspecificEI,
  title={Neuron-specific enolase in the diagnosis of neuroblastoma and other small, round-cell tumors in children.},
  author={Michael Tsokos and Ritva Ilona Linnoila and Roma S. Chandra and Timothy Triche},
  journal={Human pathology},
  year={1984},
  volume={15 6},
  pages={575-84}
}
Immunocytochemical staining for neuron-specific enolase (NSE) was performed in 44 round-cell tumors from children by the improved immunoglobulin-enzyme bridge method with antiserum against NSE. The tumors studied consisted of 15 neuroblastomas showing various degrees of histologic differentiation, 13 Ewing's sarcomas, ten soft tissue sarcomas of diverse origin, and six lymphomas of bone and soft tissues. Neuron-specific enolase was detected in all neuroblastomas, irrespective of the degree of… CONTINUE READING

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