Neuron-semiconductor chip with chemical synapse between identified neurons.

@article{Kaul2004NeuronsemiconductorCW,
  title={Neuron-semiconductor chip with chemical synapse between identified neurons.},
  author={Rauf-ur Rashid Kaul and Naweed I Syed and Peter Fromherz},
  journal={Physical review letters},
  year={2004},
  volume={92 3},
  pages={
          038102
        }
}
Noninvasive electrical stimulation and recording of neuronal networks from semiconductor chips is a prerequisite for the development of neuroelectronic devices. In a proof-of-principle experiment, we implemented the fundamental element of such future hybrids by joining a silicon chip with an excitatory chemical synapse between a pair of identified neurons from the pond snail. We stimulated the presynaptic cell (VD4) with a chip capacitor and recorded the activity of the postsynaptic cell (LPeD1… CONTINUE READING
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