Neuron restrictive silencer factor as a modulator of neuropeptide gene expression

@article{Quinn2002NeuronRS,
  title={Neuron restrictive silencer factor as a modulator of neuropeptide gene expression},
  author={J. M. P. Quinn and Vivien Jill Bubb and Zoe V. Marshall-Jones and Judy M Coulson},
  journal={Regulatory Peptides},
  year={2002},
  volume={108},
  pages={135-141}
}
We hypothesize that the transcription factor neuron restrictive silencer factor (NRSF) is an important determinant of the expression of the preprotachykinin (PPTA) gene (encoding substance P and Neurokinin A) and arginine vasopressin (AVP) both in neuronal and nonneuronal cells. NRSF, a zinc finger repressor protein, binds the NRSE motif found in many neuronal specific genes at a variety of promoter locations. However, it is found in a similar location at the major transcriptional start site… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

Similar Papers

Loading similar papers…