Neuromyelitis optica spectrum disorder in patients with connective tissue disease and myelitis.

Introduction Neuromyelitis optica (NMO) is a demyelinating, organspecific, autoimmune disease that preferentially targets the optic nerve and spinal cord. The clinical syndrome was first described by Devic and Gault in 1894, and was considered a variant of multiple sclerosis (MS). A resurgence of interest has followed the recent identification of a disease… CONTINUE READING