Neuromyelitis optica and multiple sclerosis in sisters.

  title={Neuromyelitis optica and multiple sclerosis in sisters.},
  author={Jose Antonio Cabrera-Gomez and L Ram{\'o}n-P{\'e}rez and Albert Saiz and P Llerena-Fern{\'a}ndez and L Fern{\'a}ndez-Fern{\'a}ndez and Guadalupe Ercilla and D Grass-Fern{\'a}ndez and Mar{\'i}a de Los Angeles Robinson-Agramonte and K Romero-Garc{\'i}a and R Mac{\'i}as-Betancourt and R Galvizu-S{\'a}nchez and C Otero-Motol{\'a} and M Sojo-G{\'o}mez and C Aguilar-Arias and Ml Rodr{\'i}guez-Cordero and Alina Gonz{\'a}lez-Quevedo},
  journal={Multiple sclerosis},
  volume={15 2},
INTRODUCTION The association of neuromyelitis optica (NMO) and multiple sclerosis (MS) has been reported, but details of the cases were not described. We report two Venezuelan Caucasian sisters with human leukocyte antigen (HLA) typing. RESULTS Patient 1 fulfilled McDonald, et al. criteria with HLA A*24; B*07,*15; DRB1*01,*16 (DR2 positive). Patient 2 fulfilled the NMO revised criteria of Wingerchuck, et al. with HLA A*02,*24; B*07,*40; DRB1*04,*08, similar to Canadian aboriginal NMO cases… CONTINUE READING
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