Neuromyelitis optica (Devic's disease) in a patient with syphilis.

  title={Neuromyelitis optica (Devic's disease) in a patient with syphilis.},
  author={Robert A. Wilcox and James N C Burrow and Mark Slee and Jamie Craig and Dominic Thyagarajan},
  journal={Multiple sclerosis},
  volume={14 2},
The patient initially presented with bilateral optic neuritis and periventricular cranial MRI abnormalities in the context of syphilis. Blood was positive but cerebrospinal fluid testing was negative for specific syphilis markers and he was oligoclonal cerebrospinal fluid (CSF) band negative. He initially responded well to penicillin and corticosteriod treatment, but went on to develop the clinical syndrome of neuromyelitis optica (NMO). Testing for the presence of the serum autoantibody for… CONTINUE READING