Neuromuscular blocking effects of an alkaloidal extract from Inula royleana: contractile and electrical studies on amphibian skeletal muscle in vitro.

Abstract

The neuromuscular blocking properties of an alkaloidal extract from the root of Inula royleana have been investigated in vitro using a combination of mechanical and electrophysiological approaches. Neurogenic twitches of the frog sartorius were profoundly inhibited by concentrations of the extract > or = 20 micrograms/ml, being reduced to 50% of control… (More)

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@article{Manchanda2000NeuromuscularBE, title={Neuromuscular blocking effects of an alkaloidal extract from Inula royleana: contractile and electrical studies on amphibian skeletal muscle in vitro.}, author={Ranjit Manchanda and S. Venkataprasad Bhat and B. Mehta and Jeyachandran Karunakaran and K. Venkateswarlu}, journal={Indian journal of physiology and pharmacology}, year={2000}, volume={44 2}, pages={143-52} }