Neuromuscular Junction Protection for the Potential Treatment of Amyotrophic Lateral Sclerosis

@inproceedings{Krakora2012NeuromuscularJP,
  title={Neuromuscular Junction Protection for the Potential Treatment of Amyotrophic Lateral Sclerosis},
  author={Dan Krakora and Corey Macrander and Masatoshi Suzuki},
  booktitle={Neurology research international},
  year={2012}
}
Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease characterized by the progressive degeneration of upper and lower motor neurons (MNs), leading to muscular atrophy and eventual respiratory failure. ALS research has primarily focused on mechanisms regarding MN cell death; however, degenerative processes in the skeletal muscle, particularly involving neuromuscular junctions (NMJs), are observed in the early stages of and throughout disease progression. According to the "dying-back… CONTINUE READING
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The role of glial cells in the formation and maintenance of the neuromuscular junction

  • C. P. Ko
  • Muscle & Nerve
  • 2012

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