Neuromuscular Electrical Stimulation as a Method to Maximize the Beneficial Effects of Muscle Stem Cells Transplanted into Dystrophic Skeletal Muscle

@inproceedings{Distfano2013NeuromuscularES,
  title={Neuromuscular Electrical Stimulation as a Method to Maximize the Beneficial Effects of Muscle Stem Cells Transplanted into Dystrophic Skeletal Muscle},
  author={Giovanna Dist{\'e}fano and Ricardo Jos{\'e} Ferrari and Christopher Weiss and Bridget M. Deasy and Michael L. Boninger and G. Kelley Fitzgerald and Johnny Huard and Fabrisia Ambrosio},
  booktitle={PloS one},
  year={2013}
}
Cellular therapy is a potential approach to improve the regenerative capacity of damaged or diseased skeletal muscle. However, its clinical use has often been limited by impaired donor cell survival, proliferation and differentiation following transplantation. Additionally, functional improvements after transplantation are all-too-often negligible. Because the host microenvironment plays an important role in the fate of transplanted cells, methods to modulate the microenvironment and guide… CONTINUE READING