Neuromodulation reduces urinary frequency in rats with hydrochloric acid-induced cystitis.

@article{Wang2000NeuromodulationRU,
  title={Neuromodulation reduces urinary frequency in rats with hydrochloric acid-induced cystitis.},
  author={Yang Wang and Yunhua Zhou and Mohammed Sherif Mourad and Magdy Hassouna},
  journal={BJU international},
  year={2000},
  volume={86 6},
  pages={726-30}
}
OBJECTIVE To evaluate the effect of sacral neuromodulation on interstitial cystitis (IC) and determine the underlying mechanism of neuromodulation in the treatment of IC. Materials and methods Twenty Sprague-Dawley rats (body weight 220-250 g) were randomly divided into four equal groups; normal controls, a sham treatment (IC induced by 0.4 mol/L HCl, + saline), a second sham treatment (HCl-induced IC + acetic acid) and a stimulated group (HCl-induced IC + acetic acid, with electrical… CONTINUE READING