Neuromedin B stimulates the hypothalamic-pituitary-gonadal axis in male rats.

@article{Boughton2013NeuromedinBS,
  title={Neuromedin B stimulates the hypothalamic-pituitary-gonadal axis in male rats.},
  author={Carol Boughton and Subhash A. Patel and Emily L Thompson and Michael Ty Patterson and Annette E. Curtis and Anjali Amin and Ke Chen and Mohammad A. Ghatei and Stephen R. Bloom and Kevin Graeme Murphy},
  journal={Regulatory peptides},
  year={2013},
  volume={187},
  pages={6-11}
}
Neuromedin B (NMB) is a highly conserved bombesin-related peptide found in mammals. NMB mRNA is detected in the central nervous system (CNS) and is highly expressed in the rat hypothalamus, in particular the medial preoptic area and the arcuate nucleus. The mammalian bombesin family of receptors consists of three closely related G protein coupled receptors, BB1, BB2 and BB3. The BB1 receptor subtype has the highest affinity for NMB. NMB has well documented roles in the regulation of the thyroid… CONTINUE READING