Neurolysin knockout mice generation and initial phenotype characterization.

Abstract

The oligopeptidase neurolysin (EC 3.4.24.16; Nln) was first identified in rat brain synaptic membranes and shown to ubiquitously participate in the catabolism of bioactive peptides such as neurotensin and bradykinin. Recently, it was suggested that Nln reduction could improve insulin sensitivity. Here, we have shown that Nln KO mice have increased glucose… (More)
DOI: 10.1074/jbc.M113.539148

Topics

13 Figures and Tables

Slides referencing similar topics