Neurolymphomatosis in Waldenström's macroglobulinaemia.

  title={Neurolymphomatosis in Waldenstr{\"o}m's macroglobulinaemia.},
  author={S Abad and Anne Marie Zagdanski and Sabine Br{\'e}chignac and Brigitte Thioli{\`e}re and Jean Claude Brouet and Xavier Mariette},
  journal={British journal of haematology},
  volume={106 1},
We report four patients with Waldenström's macroglobulinaemia with an unusual neurologic complication, neurolymphomatosis, characterized by meningeal and root nerve infiltration by lymphoplasmacytic cells. Patients presented with rapidly progressive leg proximal weakness. Examination of cerebrospinal fluid disclosed lymphoplasmacytic cells. Magnetic resonance imaging of the lumbar spine was suggestive of a tissular infiltration of leptomeninges and nerve roots. Chemotherapy and irradiation of… CONTINUE READING

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