Neurological diseases: Targeting programmed cell death in neurodegenerative diseases

@article{Vila2003NeurologicalDT,
  title={Neurological diseases: Targeting programmed cell death in neurodegenerative diseases},
  author={Miquel Vila and Serge Przedborski},
  journal={Nature Reviews Neuroscience},
  year={2003},
  volume={4},
  pages={365-375}
}
Molecular pathways of programmed cell death (PCD) are activated in various neurodegenerative disorders including Parkinson's disease, amyotrophic lateral sclerosis and Huntington's disease. In these diseases, PCD might be pathogenic, and targeting it might mitigate neurodegeneration. To identify potential neuroprotective targets within the PCD machinery, the expression and activity of some of its components have been altered by genetic or pharmacological means in experimental models of… 
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525 Citations
Highly Influential Citations
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525 Citations

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