• DOI:10.1038/nrn1100
Corpus ID: 33018251

Neurological diseases: Targeting programmed cell death in neurodegenerative diseases

@article{Vila2003NeurologicalDT,
  title={Neurological diseases: Targeting programmed cell death in neurodegenerative diseases},
  author={M. Vila and S. Przedborski},
  journal={Nature Reviews Neuroscience},
  year={2003},
  volume={4},
  pages={365-375}
}

M. Vila, S. Przedborski

Published 2003

Biology, Medicine

Nature Reviews Neuroscience

Molecular pathways of programmed cell death (PCD) are activated in various neurodegenerative disorders including Parkinson's disease, amyotrophic lateral sclerosis and Huntington's disease. In these diseases, PCD might be pathogenic, and targeting it might mitigate neurodegeneration. To identify potential neuroprotective targets within the PCD machinery, the expression and activity of some of its components have been altered by genetic or pharmacological means in experimental models of… CONTINUE READING

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