Neurologic recovery and improved detrusor contractility using muscle-derived cells in rat model of unilateral pelvic nerve transection.

@article{Kwon2005NeurologicRA,
  title={Neurologic recovery and improved detrusor contractility using muscle-derived cells in rat model of unilateral pelvic nerve transection.},
  author={Dong Deuk Kwon and Brandon S. Minnery and Yongtae G. Kim and Jang Hwan Kim and Fernando de Miguel and Naoki Yoshimura and Michael B Chancellor},
  journal={Urology},
  year={2005},
  volume={65 6},
  pages={1249-53}
}
OBJECTIVES To create a model of peripheral neuropathy and explore the potential of using muscle-derived cells (MDCs) to facilitate the regeneration of autonomic nerves and improve bladder function. Damage to the peripheral nerves that innervate the bladder from radical pelvic surgery is refractory to the currently available treatments. METHODS Rat MDCs were isolated from the gastrocnemius muscle using the preplate technique. The unilateral pelvic nerve was cut in female Sprague-Dawley rats… CONTINUE READING
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