Neurologic complications after melarsomine dihydrochloride treatment for Dirofilaria immitis in three dogs.

@article{Hettlich2003NeurologicCA,
  title={Neurologic complications after melarsomine dihydrochloride treatment for Dirofilaria immitis in three dogs.},
  author={Bianca Felicitas Hettlich and Kennedy Ryan and Robert Loring Bergman and Steven L. Marks and Barbara C. Lewis and Anne Marie Bahr and Joan R Coates and Joanne K. Mansell and Claudia L. Barton},
  journal={Journal of the American Veterinary Medical Association},
  year={2003},
  volume={223 10},
  pages={
          1456-61, 1434
        }
}
Melarsomine dihydrochloride is highly effective against both sexes of adult and L5 Dirofilaria immitis. Common adverse reactions include injection site irritation and reluctance to move. Neurologic complications associated with i.m. injection of melarsomine dihydrochloride for treatment of heartworm disease in 3 dogs are described. Different degrees of neurologic complications have been identified; the pathophysiologic features are unknown. It is speculated that the compound migrates out of the… CONTINUE READING

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