Neurologic abnormalities of Lyme disease: successful treatment with high-dose intravenous penicillin.

@article{Steere1983NeurologicAO,
  title={Neurologic abnormalities of Lyme disease: successful treatment with high-dose intravenous penicillin.},
  author={Allen C. Steere and Andrew R. Pachner and Stephen E. Malawista},
  journal={Annals of internal medicine},
  year={1983},
  volume={99 6},
  pages={767-72}
}
Twelve patients were treated with high-dose intravenous penicillin for neurologic abnormalities of Lyme disease. Headache, stiff neck, and radicular pain usually began to subside by the second day of therapy and were often gone by 7 to 10 days. Five of the 12 patients continued to have intermittent mild headache for several more weeks, but no patient relapsed after therapy was stopped. Compared to 15 previous patients treated with prednisone alone, the duration of meningitic syndrome was… CONTINUE READING