Neurolin Ig Domain 2 Participates in Retinal Axon Guidance and Ig Domains 1 and 3 in Fasciculation

@article{Leppert1999NeurolinID,
  title={Neurolin Ig Domain 2 Participates in Retinal Axon Guidance and Ig Domains 1 and 3 in Fasciculation },
  author={Christian A. Leppert and Heike Diekmann and C Nliranjan Paul and Ute Laessing and Monika Marx and Martin Bastmeyer and Claudia A.O. Stuermer},
  journal={The Journal of Cell Biology},
  year={1999},
  volume={144},
  pages={339 - 349}
}
The optic disk-directed growth of retinal ganglion cell axons is markedly disturbed in the presence of polyclonal antineurolin antibodies, which mildly affect fasciculation (Ott, H., M. Bastmeyer, and C.A.O. Stuermer, 1998. J. Neurosci. 18:3363-3372). New monoclonal antibodies (mAbs) against goldfish neurolin, an immunoglobulin (Ig) superfamily cell adhesion/recognition molecule with five Ig domains, were generated to assign function (guidance versus fasciculation) to specific Ig domains. By… CONTINUE READING

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