Neuroligin 2 is exclusively localized to inhibitory synapses.

  title={Neuroligin 2 is exclusively localized to inhibitory synapses.},
  author={Frederique Varoqueaux and St{\'e}phane Jamain and Nils Brose},
  journal={European journal of cell biology},
  volume={83 9},
Neuroligins are cell adhesion proteins that are thought to instruct the formation and alignment of synaptic specializations. The three known rodent neuroligin isoforms share homologous extracellular acetylcholinesterase-like domains that bridge the synaptic cleft and bind beta-neurexins. All neuroligins have identical intracellular C-terminal motifs that bind to PDZ domains of various target proteins. Neuroligin 1 is specifically localized to glutamatergic postsynaptic specializations. We show… CONTINUE READING
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