Neuroleptic malignant syndrome and mivacurium: a safe alternative to succinylcholine?

  title={Neuroleptic malignant syndrome and mivacurium: a safe alternative to succinylcholine?},
  author={Dr. Michael J. Kelly and Sorin J. Brull},
  journal={Canadian journal of anaesthesia = Journal canadien d'anesthesie},
  volume={41 9},
Neuroleptic malignant syndrome (NMS) and malignant hyperthermia (MH) may have a common pathogenic mechanism; therefore, it has been suggested that known triggering agents for MH (such as succinylcholine) should be avoided in patients with NMS. Electroconvulsive therapy (ECT) continues to play a major therapeutic role in contemporary psychiatry, and succinylcholine has been the muscle relaxant of choice in attenuating violent muscle contractions induced by ECT. Mivacurium is a non-depolarizing… CONTINUE READING
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