Neuroleptic drugs in the human brain
@article{Kornhuber2006NeurolepticDI, title={Neuroleptic drugs in the human brain}, author={Johannes Kornhuber and Jens Wiltfang and Peter Franz Riederer and Stefan Bleich}, journal={European Archives of Psychiatry and Clinical Neuroscience}, year={2006}, volume={256}, pages={274-280} }
After discontinuation of neuroleptic agents, their effects are still present for a long time. The exact underlaying mechanisms are still unclear. In two previous studies we measured the concentrations and region-specific distribution of haloperidol (Kornhuber et al. 1999) and levomepromazine (Kornhuber et al. 2006) in postmortem human brain tissues. The aim of the present paper is to compare the results of these two studies. Even after short-term treatment, haloperidol and levomepromazine…
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